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The 3WJ RNA construct folds in the presence of Mg2+ and binds protein S15. (A) The minimal binding site for 30S ribosomal protein S15 is a 3WJ located within the central domain of the 16S rRNA (23,29). (B) In the presence of metal ions, the junction folds such that helices 21 and 22 stack coaxially, while helices 20 and 22 dock (22). S15 preferentially binds the folded form (26).
