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pHi alters the single-channel activity of CFTR. A–D, single channel current amplitude (i), open probability (Po), mean burst duration (MBD), and interburst interval (IBI) of wild-type CFTR at different pHi values. Data are means ± S.E. (n = 4–14). The asterisks indicate values that are significantly different from the control value (p < 0.05). Note the break in the ordinate in A.
