TABLE 1.
Effect of HSP RNAi inhibition on DAF-16 nuclear export
| C. elegans strain | Cosmid no. | Gene | Cytosolic (%)a | Nb |
|---|---|---|---|---|
| TJ356 | Vector | 87.4 | 119 | |
| Y53C10A.12 | hsf-1 0 | 25 | ||
| C47E8.5 | daf-21/hsp90 | 96 | 24 | |
| C12C8.1 | hsp70 | 97.7 | 44 | |
| F26D10.3 | hsp-1 | 0 | 30 | |
| F44E5.4 | hsp70 | 96.4 | 56 | |
| F44E5.5 | hsp70 | 82.7 | 58 | |
| C30C11.4 | hsp110 | 96 | 74 | |
| F08H9.3 | hsp16 | 96 | 25 | |
| F08H9.4 | hsp16 | 84 | 25 | |
| F43D9.4 | sip-1 | 100 | 64 | |
| C09B8.6 | hsp25 | 98.4 | 62 |
a Percent of animals that displayed cytosolic DAF-16:GFP at 24 h of recovery from heat shock.
b N, total number of worms used for each RNAi.