mRNA and protein expression of connexin 40, 43, and 45. A, results of real time PCR analysis of connexin 40, 43, and 45. Values are change relative to each control (using atria at 4 weeks of age as control) and expressed as mean ± S.E. *, p < 0.05; **, p < 0.01, n = 6 in each group. B, upper, representative immunoblots of connexin 40, 43, and 45 in atria and ventricles of control mice and LKB1-KO mice. Lower, densitometric analysis of connexin 40, 43, and 45. The expression levels were quantified and are expressed as change relative to 4-week-old control atria. Values are change relative to each control (using atria at 4 weeks of age as control) and are expressed as mean ± S.E. *, p < 0.05; **, p < 0.01, n = 6 in each group.