Table 5. Haplotype frequencies of SNPs in TLR4.
| Haplotype | Frequency, n (%) | p (SUvs.SN) | p (SUvs.C) | p (SNvs.C) | ||
|---|---|---|---|---|---|---|
| Sarcoid uveitis n=196 | Sarcoid non-uveitis n=27 | Controls n=206 | ||||
| TAGCGGAA | 80 (40.8) | 10 (37.0) | 75 (36.4) | 0.707 | 0.364 | 0.949 |
| TAGCGCAA | 43 (21.9) | 6 (22.2) | 50 (24.3) | 0.973 | 0.579 | 0.815 |
| CGATTGAA | 23 (11.7) | 3 (11.1) | 32 (15.5) | 1.000* | 0.268 | 0.593* |
| CGATTGGA | 27 (13.8) | 6 (22.2) | 25 (12.1) | 0.247 | 0.624 | 0.147 |
| CGATTGGG | 16 (8.2) | 2 (7.4) | 20 (9.7) | 1.000* | 0.588 | 0.757* |
| CGATTCAA | 3 (1.5) | 0 (0.0) | 2 (1.0) | 1.000* | 0.678* | 1.000* |
In the table, SNP represents single-nucleotide polymorphism and TLR4 represents toll-like receptor 4. Position is the distance from the short arm telomere. Haplotypes with frequency less than 1% are not listed. P values were calculated with the χ2 test using a 2×2 contingency table. In the table, SUvs.SN represents sarcoid uveitis versus sarcoid non-uveitis, SUvs.C represents sarcoid uveitis versus control, and SNvs.C represents sarcoid non-uveitis versus control. The asterisk indicates calculation using Fisher's Exact Test.