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Wheel running over the course of the study. Distance run (km/day) (± S.E.) shown separately for C57BL/6J (open symbol; n = 12 males) and B6D2F1/J mice (closed symbol; n = 3 males and 3 females). The first 10 days, mice received daily injections of 50 mg/kg BrdU to label dividing cells. The last 10 days, mice were tested on water maze then rotarod, during the light phase of the light/dark cycle when levels of wheel running are negligible.
