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. Author manuscript; available in PMC: 2011 Jan 1.
Published in final edited form as: Breast Cancer Res Treat. 2009 Feb 11;119(1):63–70. doi: 10.1007/s10549-009-0330-4

Figure 1. Schematic representation of the shared human αB-crystallin/HspB2 promoter and conservation of the putative ETS-binding site (EBS).

Figure 1

(A) Using the MOTIF-search platform, we performed a bioinformatics analysis of the shared human αB-crystallin/HspB2 promoter spanning the region between the start ATG for each gene. The search identified published (bold) transcriptional regulators of αB-crystallin, as well as additional putative (italics) regulators, including Ets1. (B) Alignment of the putative EBS in the human αB-crystallin promoter with the corresponding region from other species.