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. Author manuscript; available in PMC: 2011 Jan 1.
Published in final edited form as: J Infect Dis. 2010 Jan 1;201(1):20–31. doi: 10.1086/648735

Figure 5.

Figure 5

TST positivity is associated with upregulation of CTLA-4 but not PD-1 mRNA. PBMC from TST+ (n = 10) and TST− (n = 10) patients were stimulated with PPD (10 μg/ml), Mtb CFA (10 μg/ml), or anti-CD3 (5 μg/ml) for 24 h, and CTLA-4 and PD-1 levels were measured by real-time RT-PCR. Results are shown as fold change over media control. P values were calculated using the Mann-Whitney test and only statistically significant P values are shown.