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. Author manuscript; available in PMC: 2010 Oct 1.
Published in final edited form as: Drug Alcohol Depend. 2009 Jul 9;104(3):220–227. doi: 10.1016/j.drugalcdep.2009.04.023

Table 2.

Urinary cotinine, expired carbon monoxide, self-reported smoking, and Questionnaire on Smoking Urges (QSU-brief) outcomes, covarying for baseline, by treatment group

DCS
Mean (SD)
Placebo
Mean (SD)
Total
Mean (SD)
F p-value
Urinary Cotinine (ng/mL)
     Experimental session 1* 1492.6 (677.2) 2530.3 (1830.3) 2032.2 (1471.7) .36 .55
     1-week follow-up 1509.1 (1026.1) 2135.2 (1353.1) 1822.1 (1214.8) .36 .55
     Experimental session 2 1602.5 (680.5) 1441.2 (937.0) 1512.8 (813.8) 3.1 .10
     4-week follow-up 1645.5 (1180.8) 2062.6 (1091.1) 1877.6 (1117.9) .02 .89
Expired Carbon Monoxide (CO)
     Experimental session 1 8.2 (5.3) 12.6 (5.6) 10.6 (5.8) 2.8 .11
     1-week follow-up 10.2 (3.9) 16.8 (8.8) 13.7 (7.6) 8.3 .01
     Experimental session 2 6.4 (3.5) 10.9 (7.1) 8.9 (6.1) 2.6 .13
     4-week follow-up 11.1 (4.8) 17.6 (9.9) 14.7 (8.5) 4.2 .06
# cigarettes smoked per day
     1-week follow-up 10.3 (6.3) 13.9 (12.7) 12.0 (9.7) .06 .80
     4-week follow-up 9.9 (7.7) 11.0 (9.2) 10.4 (8.2) .35 .56
QSU-brief
  1-week follow-up n = 10 n = 11
     Factor 1 12.9 (9.1) 16.9 (7.4) 15.0 (8.3) 1.2 .28
     Factor 2 5.0 (5.6) 5.4 (2.1) 5.2 (4.1) .04 .84
  4-week follow-up n = 7 n = 10
     Factor 1 10.3 (6.3) 12.5 (5.9) 11.6 (6.0) .55 .47
     Factor 2 4.0 (2.6) 5.0 (2.6) 4.5 (2.6) .48 .50
QSU-brief§ DCS Placebo Group
t (p-value)
Time
t (p-value)
Group × Time
t (p-value)
Experimental session #1 n = 12 n = 13
  Factor 1 −.66 (p = .51) 7.1 (p < .001) −1.8 (p = .08)
     Time point 1 23.6 26.2
     Time point 11 13.1 19.9
Experimental session #1
  Factor 2 −.36 (p = .72) 5.4 (p < .001) −.90 (p = .37)
     Time point 1 7.1 7.6
     Time point 11 3.6 5.1
Experimental session #2 n = 8 n = 10
  Factor 1 −.98 (p = .34) 4.9 (p < .001) .25 (p = .80)
     Time point 1 17.5 21.7
     Time point 11 12.6 16.2
Experimental session #2
  Factor 2 −1.6 (p = .14) −.86 (p = .39) 1.9 (p = .06)
     Time point 1 3.9 5.7
     Time point 11 4.3 4.7
*

At experimental session 1, n = 12 in the DCS group and n = 13 in the placebo group. At experimental session 2, n = 8 in the DCS group and n = 10 in the placebo group. At 1 week follow-up, n = 11 (total n = 22) in each treatment group, and at 4 week follow-up, n = 8 in the DCS group and n = 10 in the placebo group.

§

QSU-brief at experimental session 1 and 2 is the estimated self-reported urge-to-smoke mean ratings of eleven QSU-brief measures administered every 40 minutes throughout each experimental session. We presented only the estimated means for the QSU-brief delivered at time point 1 and time point 11 to show differences between scores at the beginning and end of the QSU-brief administration.

Factor 1 of the QSU-brief represents smoking as the result of the ‘desire to smoke’, while Factor 2 represents smoking to ‘relieve negative affect’.