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Effects of thioperamide and MK-801 on A.) baseline (“No startle”) activity and B.) auditory startle in the sensorimotor testing. Both doses of MK-801 enhanced auditory startle regardless of thioperamide pretreatment, as indicated by an asterisk. Data represent average force (expressed in newtons) ± s.e.m during no startle and startle trials. n = 12 animals per group.
