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Antiinflammatory effects of PEA and synthetic PPAR-α agonist GW7647. Effects of (A) PEA or (B) GW7647 (each at 50 μg per sponge) on leukocyte infiltration in s.c. sponges instilled with vehicle (sterile saline, 0.1 mL) or carrageenan (Carr, 1%) in wild-type C57BL/6J (+/+) and PPAR-α−/− (−/−) mice. **, P < 0.01 vs. vehicle; ***, P < 0.001 vs. vehicle; ###, P < 0.001 vs. carrageenan/vehicle (n = 5–6).
