Figure 3.
The relative change in the mRNA expression at various stages of the myelination process in Schwann cell/neuronal cocultures. The relative mRNA expression for myelin basic protein (
), cytochrome P450scc (■), 3β-HSD (
), and the progesterone receptor (
) were measured during various stages of the myelination process. The fold change in mRNA expression is relative to premyelinating cultures at 3 days after seeding. Schwann cells were induced to myelinate 7 days after seeding (day 0) by the addition of ascorbic acid.