Table 3.
Fibroblast cell lines | % NKp44 m.f.i. inhibition (Fibr/NS398)* | PGE2 (pg/ml) without NK | PGE2 (pg/ml) with NK | |
---|---|---|---|---|
Patient #1 | TF1 | 69/48 | 4,294.6 | 6,916 |
Patient #2 | TF2 | 84/59 | 1,802 | 4,617 |
Patient #3 | TF3 | 62/n.d. | 1,580 | 6,810 |
Patient #4 | TF4 | 95/0 | 6,616 | 6,650 |
Patient #5 | TF5 | 71/n.d. | n.d. | n.d. |
Patient #6 | TF6 | 71/70 | 296 | 1,302 |
Patient #7 | TF7 | 55/18 | 557.3 | 1,033.3 |
Patient #8 | TF8 | 61/0 | 344 | 6,092 |
Patient #9 | TF9 | 58/n.d. | 6,710 | 6,812 |
Patient #10 | TF10 | 92/44 | 3,041.3 | 6,622 |
Patient #11 | TF11 | 72/55 | 4,677 | 15,107 |
Healthy #1 | HF1 | 0 | 25.4 | 41.4 |
Healthy #2 | HF2 | 0 | 29.2 | 394.7 |
Healthy #3 | CRL-2106 | 9/2 | 37.7 | 88.7 |
Healthy #4 | CRL-2201 | 41/38 | 212.2 | 231.2 |
*values indicate the % of NKp44 m.f.i. inhibition induced by fibroblasts either in the absence or in the presence of PGE2 inhibitor NS398.