Fig. 3.

Rats performing overtraining sessions maintain high levels of CA3 LG modulation by theta phase. (A) (i) Animal's performance during an overtraining session. (ii) Pseudocolor scale representation of the mean LG amplitude as a function of the theta phase for each trial in the overtraining session. (iii) Mean LG amplitude per theta phase in four nonoverlapping windows of 20 trials each. These results were obtained from a representative animal (see also Fig. S4). (B) Group data results. (Upper) MI ratio between the first and last 30 trials of learning and overtraining sessions. (Lower) Normalized MI for the first and last 30 trials of learning and overtraining sessions. The normalization was done within each rat by dividing each group value by the average over the four groups. Bars represent the mean (± SEM) over rats. *, P < 0.001. (C) Pooled data results. (Upper Three Rows) Shown are the number of correct (green) and error (red) trials pooled among all animals in nonoverlapping 10 trial blocks for learning (Left) and overtraining (Right) sessions, and the percentage of correct trials in each block. The mean MI value in each trial block is shown (black squares). (Lower Row) Also shown are the mean MI in each trial block separated for correct (green squares) and error (red squares) trials. Error bars represent SEM.