Figure 4.
A significant Age × Sex interaction effect was found for activation of the hippocampus (Hip) while participants appraised how they thought peers would evaluate them, specifically, while viewing peers of high interest versus peers of low interest. (a) Cross-hairs centered on the maximum intensity value (Talairach coordinates: x = 33, y = −16, z = −11), t(30) = −4.65, p < .001, for the cluster in the right Hip. (b) As age increased, hip activation increased in females but did not change in males. Data were extracted at functional magnetic resonance imaging (fMRI) acquisition during appraisal ratings. Each participant’s data were converted to percentage signal change values using each participant’s voxel-wise time series mean as a baseline and averaged within the region.