Figure 6.

Subcellular location of human telomerase catalytic subunit. IMR-90 (a and b) and HeLa (c, d, e, and f) cells were simultaneously stained with Hoechst 33258 to visualize nuclei (a, c, and e) and with anti-hTERT antibodies K-370 (b, d, and f). IMR90 are nonimmortal human diploid fibroblasts that have no detectable telomerase activity. HeLa are human papillomavirus-transformed human epithelial cells that have telomerase activity. Note the punctuated hTERT expression pattern in the nucleus. (Objective was ×100.)