Table 2. Kinetic rate constants k_on and k_off of antibody wild type and Variant FS binding to FcγRIa.

MAb	kon (M−1s−1)	koff (s−1)	KD (M)	Rmax (RU)
WT	4.5×104	8.2×10−4	1.8×10−8	479
FS	2.9×104	2.1×10−3	7.4×10−8	126