TABLE 3. Irritability in Early Adolescence as Predictor of Disorders at 20-Year Follow-Up, Controlling for Scaled Symptom Scores at Baselinea.
Adjustment for Baseline Scaled Score | ||||||||
---|---|---|---|---|---|---|---|---|
Major Depressive Disorder Score | Overanxious Disorder Score | Oppositional Defiant Disorder Score | Conduct Disorder Score | |||||
Disorder in Adulthood | Odds Ratio | 95% CI | Odds Ratio | 95% CI | Odds Ratio | 95% CI | Odds Ratio | 95% CI |
Major depressive disorder | 1.26 | 0.98–1.63 | 1.37* | 1.08–1.76 | 1.3 | 0.98–1.74 | 1.31* | 1.02–1.67 |
Generalized anxiety disorder | 1.85* | 1.22–2.84 | 2.07** | 1.39–3.10 | 1.92* | 1.19–3.10 | 1.93* | 1.27–2.92 |
Dysthymia | 1.92** | 1.20–3.06 | 2.02** | 1.33–3.05 | 2.03* | 1.18–3.46 | 1.80** | 1.16–2.82 |
All logistic regression models report unit-based increases in irritability associated with increases in the odds of disorder in adulthood, adjusted for age, sex, and family socioeconomic status. Imputed N=776.
p<0.05;
p<0.01.