Skip to main content
. Author manuscript; available in PMC: 2009 Dec 11.
Published in final edited form as: Am J Psychiatry. 2009 Jul 1;166(9):1048–1054. doi: 10.1176/appi.ajp.2009.08121849

TABLE 3. Irritability in Early Adolescence as Predictor of Disorders at 20-Year Follow-Up, Controlling for Scaled Symptom Scores at Baselinea.

Adjustment for Baseline Scaled Score

Major Depressive Disorder Score Overanxious Disorder Score Oppositional Defiant Disorder Score Conduct Disorder Score




Disorder in Adulthood Odds Ratio 95% CI Odds Ratio 95% CI Odds Ratio 95% CI Odds Ratio 95% CI
Major depressive disorder 1.26 0.98–1.63 1.37* 1.08–1.76 1.3 0.98–1.74 1.31* 1.02–1.67
Generalized anxiety disorder 1.85* 1.22–2.84 2.07** 1.39–3.10 1.92* 1.19–3.10 1.93* 1.27–2.92
Dysthymia 1.92** 1.20–3.06 2.02** 1.33–3.05 2.03* 1.18–3.46 1.80** 1.16–2.82
a

All logistic regression models report unit-based increases in irritability associated with increases in the odds of disorder in adulthood, adjusted for age, sex, and family socioeconomic status. Imputed N=776.

*

p<0.05;

**

p<0.01.