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. Author manuscript; available in PMC: 2010 Dec 1.
Published in final edited form as: Thromb Haemost. 2009 Dec;102(6):1183–1193. doi: 10.1160/TH09-04-0273

Figure 2. Anticoagulant activity of heparin (A), high- (B) and low- (C) molecular-weight sulfated galactans based on APTT, performed with normal human plasma (●), antithrombin- (■), heparin cofactor II- (▲) or both serpins-free plasmas (○).

Figure 2

A mixture of 100 μL of normal or serpin-free human plasma and increasing concentrations of sulfated polysaccharide were incubated with 100 μL of APTT reagent. After 2 min of incubation at 37°C, 100 μL of 25 mM CaCl2 was added to the mixtures, and the clotting time was recorded. The results are expressed as ratios of clotting time in the presence (T1) and in the absence (T0) of sulfated polysaccharide. The panels show mean±SD, n=3. (A) *p < 0,05 for ▲, ■ or ○ vs. ●; (B) *p < 0,05 for ■ vs. ●; (C) NS, not significant (p > 0,05).