Table 3.

Inhibition of carbonic anhydrase type II by topiramate according to different assay methods

Method	Ki	Ref
pH shift method (Supuran's group)	10 nm	[34]
pH shift method (Maryannoff's group)	500 nm	[33]
Esterase assay	430 nm	[33]
ThermoFluor assay	500 nm	[47]