Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
The simulated concentrations time-course after a single dose of 600 mg efavirenz in four typical subjects, based on the final efavirenz pharmacogenetic/pharmacokinetic model. Wild-type: CYP2B6516G/G, CYP2B6*11G/G and ABCB1 rs3842A/A (19.0%). Homozygous mutant: CYP2B6516T/T, CYP2B6*11T/T and ABCB1 rs3842 G/G (2.7%)
