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Effect of UGT2B15 D85Y genotype on plasma oxazepam concentrations in 30 subjects administered a 15-mg oral dose of oxazepam. Shown at each time point after administration are the mean (± SE) concentrations for subjects with either 85DD (n= 6), DY (n= 20) or 85YY (n= 4) genotypes. Derived pharmacokinetic parameters are given in Table 1. D/D (–•–); D/Y (–○–); Y/Y (–▾–)
