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Km values for cosubstrates and two peptide substrates of the recombinant human lysyl hydroxylases 3 and 1
| Cosubstrate or substrate |
Km, μM
|
|
|---|---|---|
| Lysyl hydroxylase 3 | Lysyl hydroxylase 1 | |
| Fe2+ | 2 | 2 |
| 2-Oxoglutare | 100 | 100 |
| Ascorbate | 300 | 350 |
| Peptide substrate L-1* | 600 | 500 |
| Peptide substrate (IKG)3 | 800 | 700 |
Ala-Arg-Gly-Ile-Lys-Gly-Ile-Arg-Gly-Phe-Ser-Gly (19).
