Table 3.
(pg/20μl dialysate) | S/S | S/AA | S/NT79 | NT79/AA |
---|---|---|---|---|
5-HT | 5±1* | 12±2 | 10±4 | 3±0.8* |
5-HIAA | 1600±100 | 1400±184 | 800±200 | 1300±10 |
DA | 1.0±0.2 | 1.8±0.9 | 1.0±0.3 | 1.4±0.2 |
HVA | 60±20 | 100±50 | 30±20 | 400±200 |
DOPAC | 120±40 | 180±90 | 40±30 | 50±10 |
Rats were treated and samples collected as described in the legend to Figure 9. The monoamine levels were quantitated from measurements of the area under the curve (AUC) and the use of standard curves, which were generated by linear regression analyses (GraphPad Prism, GraphPad Software, Inc., La Jolla, CA, USA). The data represent the meant ± SEM of fractions collected after the second injection.
Significantly different from S/AA (P<0.05).
S=saline NT=NT79 AA=acetic acid