Fig. 4.
Cα trace and stereo view of MT1-DD and MT1-CSD structural overlap. (a) The MT1-DD (red) is shown overlapped with the corresponding domain of MTHFR (green). Corresponding α-helices and β-strands are labeled as α and β, respectively, according to numbering convention for MTHFR. (b) The small domain of MT1 (red) is shown overlapped with 1SRO (green), 1MJC (blue), and 1FJF_Q (orange). Figures were prepared with the program MOLSCRIPT.33 Residues were deleted from proteins where appropriate to simplify the diagram. Refer to text for PDB identifiers.