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. Author manuscript; available in PMC: 2010 May 15.
Published in final edited form as: J Immunol. 2009 Nov 15;183(10):6377–6386. doi: 10.4049/jimmunol.0901268

Fig. 7.

Fig. 7

Tregs suppress the extramedullary myelopoiesis in the spleen of FoxP3(-/-) scurfy mice. (A) Frequencies of FoxP3+ CD4+ T cells and FoxP3- CD4+CD69+ /CD62L+ in the spleen of ∼3 week-old FoxP3(-/-) scurfy mice transferred with Tregs at day 1 or 2 following birth compared to age-matched wild type mice and control scurfy mice. (B) Frequencies of GM-CSF+ CD4+ T cells and IL-3+ CD4+ T cells in the spleen. (C) Frequencies of lineage (CD3/CD19/CD11b)-negative c-Kit+ progenitor cells in the spleen. (D) Frequencies of CFU-GM myeloid progenitor cells in the spleen. Averages and SEM of the data obtained from 4-6 mice are shown. *,**Significant differences from wild type mice (*, P < 0.05) or FoxP3(-/-) mice (**, P < 0.05).