Figure 7. Effect of osteotrophic agents on ALP activity of adult bone-derived cells.

Isolated adult bone-derived cells were seeded at equal densities and treated with either β-estrogen (10⁻⁸ M), Prostaglandin E₂ (10⁻⁶ M) or inorganic pyrophosphate (0.5 mM) for four days. Data is presented as percent differences from control. Estrogen differentially regulates normalised ALP activity in S-Bdc and L-Bdc.