Table 1. Differentially expressed genes in skull and limb bone associated with developmental patterning, Wnt signalling, osteoporosis and ossification.
| High expression in skull | Gene Symbol | S∶L ratio | Gene Symbol | S∶L ratio | High expression in limb | Gene Symbol | S∶L ratio |
| Sfrp2 | 13.51 | Alcam | 2.58 | Btg2 | 0.49 | ||
| Cart1 | 10.76 | Eln | 2.57 | Grpca | 0.49 | ||
| Sost | 5.36 | Prelp | 2.54 | Svil | 0.48 | ||
| Amelx | 5.12 | Twist1 | 2.51 | Lect2 | 0.43 | ||
| Vdr | 4.81 | Sema5a | 2.49 | Best5 | 0.38 | ||
| Calcr | 4.66 | Bmpr2 | 2.48 | Comp | 0.38 | ||
| Ambn | 4.23 | Sp7 | 2.42 | Mmp8 | 0.29 | ||
| Wif1 | 4.17 | Ank | 2.37 | Pdlim7 | 0.24 | ||
| Gpnmb | 3.81 | Lrp4 | 2.35 | Bmp5 | 0.22 | ||
| Cd276 | 3.74 | Mmp13 | 2.32 | Ctnnb1 | 0.20 | ||
| Igfbp5 | 3.68 | Nab2 | 2.26 | Wnt16 | 0.06 | ||
| Tcf7 | 3.51 | Dlx5 | 2.22 | Hoxa5 | 0.05 | ||
| Bmp3 | 3.43 | Ptprv | 2.20 | Shox2 | 0.05 | ||
| Bmp6 | 3.29 | Enpp1 | 2.19 | Cacna1s | 0.04 | ||
| Acp5 | 3.28 | Tpp1 | 2.19 | Csrp3 | 0.04 | ||
| Nog | 3.24 | Cdh15 | 2.17 | ||||
| Frzb | 3.14 | Dlx3 | 2.16 | ||||
| Cyp26b1 | 3.04 | Lrp5 | 2.15 | ||||
| Tnfrsf11b | 2.93 | Ptn | 2.13 | ||||
| Calca | 2.92 | Cpz | 2.09 | ||||
| Pthr1 | 2.91 | Ibsp | 2.09 | ||||
| Csf1r | 2.89 | Omd | 2.08 | ||||
| Cthrc1 | 2.83 | Fgfr1 | 2.06 | ||||
| Csf1 | 2.82 | Tcf3 | 2.04 | ||||
| Plau | 2.81 | Mitf | 2.01 | ||||
| Mmp9 | 2.78 | Igf2bp2 | 2.00 | ||||
| Ctsk | 2.70 |
S∶L ratio = Skull∶Limb ratio.