FIG. 3.

Cell redifferentiation. (a) Sulfated glycosaminoglycan (sGAG) and (b) collagen type II production on a per-cell basis. Sulfated glycosaminoglycan samples are reported as pg/cell ± standard error of the mean for n = 5–8 patients. Standard error bars are shown. Collagen type II samples are the pooled results from n = 4 patients. The red dotted line separates nonserum from serum conditions. Significant differences from the basal control condition, A, are indicated: *p < 0.05, **p < 0.01, ***p < 0.005, and ****p < 0.001. CM, cells with cell-associated matrix; FRM, further removed matrix (panel a only); dex, dexamethasone; TGF-β1, transforming growth factor β1; IGF-I, insulin-like growth factor I; BMP-14, bone morphogenic protein 14; ABS, adult bovine serum.