Table 1.

Baseline Donor Characteristics of Young Healthy Donors Versus Patients with Coronary Artery Disease (CAD)

Characteristic	Healthy Donors (n = 13)	Patients with CAD (n = 13)	P-Value
Male, n (%)	9 (69)	9 (69)
Race, n (%)
White	12 (92)	10 (77)
Other (2 black, 2 Asian)	1 (8)	3 (23)
Age, mean ± SD (range)	26 ± 3 (23–31)	62 ± 11 (44–75)	<0.001
Body mass index, mean ± SD	24.3 ± 2.6	29.0 ± 4.1	0.01
Smoking history, n (%)	0	5 (39)	0.04
Diabetes, n (%)	0 (0)	7 (54)	0.005
Hypertension, n (%)	2 (15)	10 (77)	0.005
Hyperlipidemia	1 (8)	11 (85)	<0.001
Number of vessels with significant CAD, mean ± SD	—	2.1 ± 1.0
Percutaneous transluminal coronary angioplasty, n (%)	0 (0)	9 (69)	<0.001
Coronary artery bypass graft, n (%)	0 (0)	7 (54)	0.005
Medication use, n (%)
Beta blockers	0 (0)	13 (100)	<0.001
Statins	0 (0)	10 (77)	<0.001
Angiotensin-converting enzyme inhibitors	1 (8)	9 (69)	0.004

SD, standard deviation.