FIG. 4.
Integrin expression and blocking by CB-EPCs and HAECs. (A) Relative amount of adhesion integrins present on CB-EPCs and HAECs determined by flow cytometry. CB-EPCs express a significantly higher level of α5β1 compared to HAECs (*p < 0.05; n = 4). (B) Number of adherent cells after blocking α5β1, αVβ3, or both α5β1 and αVβ3 integrins with blocking antibodies. α5β1 significantly decreased adhesion compared to the control (no blocking antibodies) (*p < 0.05), both α5β1 and αVβ3 significantly decreased adhesion compared to the control (*p < 0.01), and both α5β1 and αVβ3 significantly decreased adhesion compared to α5β1 (#p < 0.05).