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Summed totals of soluble collagen found in media (A) and bulk MMP activity found in media (B) of BSMC-seeded SIS. Data are presented as mean ± SEM with n = 6 per group. * indicates p < 0.05 compared to all other groups. + indicates p < 0.05 compared to all groups except FGF-2 at 0.5 Hz. MMP, matrix metalloproteinase.
