FIG. 1.

Extracellular matrix protein microarray. (A) Diagram showing composition and position of all 64 unique compositions of collagen I, III, and IV; fibronectin (Fn); laminin (Ln); and Engelbreth-Holm-Swarm matrix (E). Number adjacent to each spot corresponds to the identity (ID) of the mixture in Table 1. Position of the pure Fn spot is indicated, and the box shows its nearest extracellular matrix (ECM) neighbors. (B) Diagram showing pattern of protein deposition for each of the six ECM proteins used to print the microarray. (C) Proteins were deposited in four replicates onto HydroGel microarray slides using a Virtek ChipWriter Pro robotic microarrayer.