Table 1.
Quantification of 14C-SIS and 14C-X-SIS Scaffold Degradation, as Measured by LSC
| Clodronate liposomes | PBS liposomes | Saline | ||
|---|---|---|---|---|
| 14C-SIS | 1 week | 1273.0 ± 63.3a–c | 683.8 ± 134.9c | 468.0 ± 227.6c |
| 2 weeks | 1214.2 ± 407.3a,b | 41.5 ± 47.3b–d | 786.0 ± 215.78a,c | |
| 14C-X-SIS | 1 week | 1115.1 ± 453.5 | 1281.0 ± 204.6 | 1026.6 ± 536.3 |
| 2 weeks | 1115.8 ± 355.8 | 1130.4 ± 156.7 | 1349.0 ± 204.6 | |
| Nonimplanted 14C-SIS | 1081.5 ± 112.8 (n = 7) |
The CPM were measured for each scaffold. Values reported as mean ± standard deviation.
a
Significant compared with PBS liposome control (p < 0.05).
b
Significant compared with saline control (p < 0.05).
c
Significant compared with nonimplanted 14C-SIS scaffold (p < 0.05).
d
Significant compared with 1-week data from the same treatment group (p < 0.05).