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. Author manuscript; available in PMC: 2009 Dec 11.
Published in final edited form as: ACS Chem Biol. 2009 Oct 16;4(10):844–854. doi: 10.1021/cb900167m

Figure 2.

Figure 2

Fluorescence-monitored titrations of compounds with HIV-1screen RNA. Titrations are plotted as the normalized change in fluorescence versus compound concentration. Data represent an average of 3 titrations, with the SEM indicated. a) Doxorubicin, red squares; idarubicin, violet triangles; butamben, green circles; and cinchonidine, blue diamonds. b) Representative data from doxorubicin competition titrations. Data from titrations into HIV-1screen alone, HIV-1screen in competition with 10-fold molar excess HIV-1Δbulge, and HIV-1screen in competition with 10-fold molar excess HIV-1wtbulge are shown as red squares, pink circles, and dark red triangles, respectively.