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. 2009 Dec;128(4):484–499. doi: 10.1111/j.1365-2567.2009.03132.x

Figure 5.

Figure 5

SIR2RP1 do not stimulate TLR2-deficient BM-DC cells. C57BL/6 WT and C57BL/6 TLR2(−/−) mice BM-DC were incubated for 24 hr with medium (thin solid line), 10 μg/ml of SIR2RP1 (thick solid line) or 1 μg/ml of LPS (dotted line) and the surface expression of CD40, CD80, CD86 and class II MHC was determined by flow cytometry analysis. The shaded line represents the correspondent isotypic control. Results are representative of one of three independent experiments.