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Response of a thalamic reticular neuron to acetyl-β-methylcholine. The thalamic reticular neuron was recorded in current clamp mode in 0.2 mM Ca2+/6 mM Mg2+ ACSF (to eliminate any possible presynaptic influences of the agonist). Bath application of 250 μM of acetyl-β-methylcholine (gray horizontal line) hyperpolarized the neuron.
