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. 2009 Oct 20;30(12):2109–2116. doi: 10.1093/carcin/bgp251

Fig. 6.

Fig. 6.

Knockdown of Abi1 expression markedly slowed tumor growth of MDA-MB-231 breast cancer cells. (A) Tumor development in murine mammary fat pad xenograft model. MDA-MB-231 control and Abi1KD cells were implanted in the mammary fat pads of NOD–SCID mice (five mice per group), and tumor growth was monitored bi-weekly by measuring tumor diameters. (B) Tumor development was also examined by measuring tumor weights 10–12 weeks post-implantation. The y-axis represents the mean ± SD of tumor weight; *P < 0.01. A representative picture of tumors from the mice injected with control (ctrl) and Abi1KD cells (kd) is shown. The data represent one of three independent experiments.