Table IV.
Diplotype analysis of significant haplotypes RAPTOR SNPs
| RAPTOR | Haplotype H2 |
Number of subject |
OR (95% CI)a | P value | |
| No. | Case (%) | Control (%) | |||
| Block 2 | 0 | 358 (44.58) | 324 (40.35) | Ref. | |
| 1 | 341 (42.47) | 363 (45.21) | 0.80 (0.65–1.00) | 0.054 | |
| 2 | 104 (12.95) | 116 (14.45) | 0.76 (0.56–1.05) | 0.100 | |
| P for trend | 0.039 | ||||
| Block 3 | 0 | 487 (60.65) | 530 (66.00) | Ref. | |
| 1 | 261 (32.50) | 244 (30.39) | 1.16 (0.93–1.46) | 0.182 | |
| 2 | 55 (6.85) | 29 (3.61) | 2.23 (1.38–3.60) | 0.001 | |
| P for trend | 0.003 | ||||
Block 2: rs7212142-rs12939076. Block 3: rs1485330-rs7217223-rs4889875-rs35544492-rs9901366-rs7501659-rs9906827-rs7208502-rs12948054-rs4062178-rs7211818-rs6565478-rs12603074-rs9915378-rs9674559. Significant associations and significant SNPs found were in bold.
a
Adjusted by age, gender, smoking status and pack year