Table 1.
Demographics and clinical characteristics of patients
| Group 1 | Group 2 | Group 3 | Group 4 | Group 5 | Group 6 | |
|---|---|---|---|---|---|---|
| TWMLL (cm3) | 0–2 | 2–4 | 4–8 | 8–16 | 16–32 | 32+ |
| n | 55/62 | 55/61 | 55/73 | 55/87 | 55/85 | 55/57 |
| Age (year) | 40.02 (5.08) | 38.06 (6.03) | 36.30 (5.78) | 39.57 (5.99) | 37.72 (5.80) | 38.44 (6.27) |
| Gender (M/F) | 30/25 | 26/29 | 33/22 | 36/19 | 30/25 | 22/33 |
| Average TWMLL (cm3) | 1.004 | 2.920 | 5.817 | 12.023 | 21.99 | 43.378 |
Multiple sclerosis patients were classified into six groups according to their TWMLL values. Note that the number of subjects retained from each group was different from the initial classification (see the denominator of the second row of the table, n). We excluded the subjects whose regional cortical thickness fell 3 SDs from the mean of their group. After this, Group 6 only included 55 subjects, which was less than other groups. Given that the multiple sclerosis brain networks were constructed by calculating the regional cortical thickness correlations across subjects, we thus selected the same number of subjects (55) for each group. Subjects were included if their TWMLL values showed minimum differences with the mean TWMLL of their group. The average TWMLL value of the included subjects for each group was shown in the bottom row of the table.