TABLE 2.

EFFECT OF THIAZOLIDINONE DERIVATIVES ON CARRAGEENAN-INDUCED PAW EDEMA

Compound code	Dose (mg/kg)	Mean paw volume at different time intervals (ml)		Percentage inhibition of edema volume (ml)
		1st h	3rd h	1st h %	3rd h %
Control	50	5.85±0.044	6.82±0.018	0.0	0.0
Nimesulide	50	4.97±0.014**	3.84±0.012**	15.1	43.7
B1	50	4.68±0.046**	5.46±0.064**	20.0	20.0
	100	4.72±0.064**	4.71±0.056**	19.4	31.0
B2	50	5.12±0.079**	4.02±0.040**	12.5	41.1
	100	4.74±0.027**	4.06±0.054**	18.9	40.5
B3	50	5.17±0.067**	4.34±0.061**	11.7	36.4
	100	5.09±0.039**	3.92±0.025**	13.0	42.6
B4	50	4.89±0.033**	4.19±0.061**	16.4	38.6
	100	4.73±0.024**	4.23±0.021**	19.1	37.9
B5	50	5.04±0.048**	4.39±0.037**	13.9	35.6
	100	4.90±0.039**	4.08±0.056**	16.2	40.2
B6	50	5.09±0.039**	4.29±0.032**	12.9	37.0
	100	4.94±0.040**	4.04±0.037**	15.5	40.8
B7	50	4.97±0.056**	4.29±0.032**	15.0	37.0
	100	4.88±0.030**	4.04±0.040**	16.6	40.8
B8	50	4.74±0.045**	4.56±0.033**	19.0	33.2
	100	4.90±0.030**	3.61±0.072**	16.3	47.1
B9	50	5.36±0.108**	4.21±0.031**	08.4	38.3
	100	4.63±0.045**	4.08±0.015**	20.9	40.2
B10	50	5.16±0.048**	4.77±0.052**	11.8	30.1
	100	5.02±0.091**	4.50±0.049**	14.2	34.1
B11	50	5.24±0.108**	4.46±0.091**	10.5	34.7
	100	5.02±0.027**	4.27±0.031**	14.2	37.4

N=6, Values are Mean±SEM

^**P<0.01(significant), values are compared with control group