TABLE 1.
ANTIMICROBIAL ACTIVITY OF THE METHANOL EXTRACTS OF STACHYS BYZANTINA, S. INFLATA, S. LAVANDULIFOLIA AND S. LAXA*
| Sample | Con. (μg/disc) | Diameter of zone of inhibition (mm) | ||||
|---|---|---|---|---|---|---|
| Bacteria | ||||||
| S. aureus (G +) | S. sanguis (G +) | E. coli (G -) | P. aeroginosa (G -) | K. pneumoniae (G -) | ||
| S. byzantina | 10 | - | - | - | - | - |
| 50 | - | 8.7 | - | - | - | |
| 100 | 8.6 | 10.1 | 8.5 | - | - | |
| 250 | 9.6 | 11.7 | 9.5 | - | 8.8 | |
| 500 | 10.9 | 12.7 | 11.1 | - | 10.1 | |
| 750 | 12.2 | 13.8 | 13.3 | 8.8 | 11.3 | |
| 1000 | 13.4 | 15.0 | 14.5 | 10.2 | 13.4 | |
| S. inflata | 10 | - | - | - | - | - |
| 50 | - | - | - | - | - | |
| 100 | - | - | - | - | - | |
| 250 | 8.3 | 8.6 | - | 9.0 | 8.7 | |
| 500 | 9.4 | 9.8 | 8.8 | 10.2 | 9.5 | |
| 750 | 10.8 | 11.2 | 9.6 | 11.3 | 10.7 | |
| 1000 | 11.9 | 12.4 | 10.7 | 12.7 | 11.7 | |
| S. lavandulifolia | 10 | - | - | - | - | - |
| 50 | - | 8.6 | - | - | - | |
| 100 | - | 9.5 | - | - | 8.5 | |
| 250 | - | 10.9 | 8.5 | 8.6 | 9.3 | |
| 500 | 8.6 | 11.7 | 9.5 | 9.7 | 10.9 | |
| 750 | 9.5 | 13.5 | 10.6 | 10.9 | 11.8 | |
| 1000 | 11.6 | 15.3 | 12.1 | 12.4 | 12.9 | |
| S. laxa | 10 | - | - | - | - | - |
| 50 | - | - | - | - | - | |
| 100 | 8.6 | - | - | - | - | |
| 250 | 10.0 | 8.6 | - | 8.5 | - | |
| 500 | 11.5 | 10.0 | - | 9.8 | 8.5 | |
| 750 | 13.2 | 11.3 | - | 11.6 | 10.1 | |
| 1000 | 14.2 | 13.4 | - | 12.6 | 12.2 | |
| Gentamicin | 50 | 37.3 | 24.0 | 31.6 | 31.0 | 28.0 |
| Amikacin | 3 | 24.9 | 19.9 | 23.8 | 15.8 | 18.0 |
| Amphotericin B | 100 | - | - | - | - | - |
*
Zone of inhibition, including the diameter of the filter paper disc (6 mm); mean value of eight independent experiments; gentamicin, amikacin and amphotericin B were used as positive controls; - no inhibition.