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. 2008 Jul-Aug;70(4):455–460. doi: 10.4103/0250-474X.44593

TABLE 6.

DRUG RELEASE KINETICS PARAMETERS OF RELEASE STUDIES THROUGH RAT SKIN

Formulation Code First order Equation Higuchi’s Equation Korsmeyer’s-Peppas Equation


R2 K R2 n
D1 0.9843 3.5×10-2 0.9356 0.9655 0.6613
D3 0.9138 1.7×10-2 0.9687 0.9621 0.6792
D5 0.9453 2.6×10-2 0.9696 0.9461 0.6160
D7 0.9592 6.0×10-2 0.9494 0.9494 0.6670