TABLE 4.
Groups | Dose mg/kg | Paw Edema Volume (ml) Mean ± SEM | |||
---|---|---|---|---|---|
1 h | 2 h | 3 h | 4 h | ||
1 | Control | 0.90±0.0367 | 0.76±0.0396 | 0.63±0.0246 | 0.56±0.0178 |
2 | 85 CO | 0.59±0.0881* | 0.44±0.0779* | 0.38±0.0545* | 0.34±0.0386* |
3 | 175 CO | 0.75±0.0208* | 0.57±0.0195* | 0.44±0.0250* | 0.41±0.0255* |
4 | 250 CO | 0.54±0.0499* | 0.31±0.0478* | 0.33±0.0402* | 0.29±0.0418 |
5 | 350 CO | 0.63±0.0225* | 0.43±0.0155* | 0.47±0.0110* | 0.44±0.0129* |
6 | 700 CO | 0.61±0.0290* | 0.49±0.0184* | 0.50±0.108 | 0.47±0.0132 |
7 | 1400 CO | 0.64±0.5050* | 0.49±0.0292* | 0.53±0.0225 | 0.49±0.0251 |
8 | Dexamethasone (0.27 mg/kg) | 0.45±0.0348* | 0.27±0.0580* | 0.29±0.0572* | 0.25±0.0407* |
All values are expressed as mean±SEM of a sample size of n=6; level of significance chosen was *p<0.05. All treated groups were compared with control group. CPM is chlorpheniramine maleate (2 mg/kg)