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. Author manuscript; available in PMC: 2010 Nov 1.
Published in final edited form as: J Neurochem. 2009 Aug 21;111(3):766–776. doi: 10.1111/j.1471-4159.2009.06353.x

Fig 2.

Fig 2

Anti-inflammatory activity of flurbiprofen and HCT-1026 in primary rat cortical astrocyte cultures. (A) iNOS activity as measured by Griess assay for NO2− in culture supernatants of primary astrocytes. Cells were pretreated 1 h with 100 μM flurbiprofen or HCT-1026 followed by induction by LPS (1 μg/ml)/IFN-γ (100 U/ml) and measurement of NO2− production at 48 h. (B) TNF-α & IL-6 production was measured by ELISA 48 h after induction by LPS/IFN-γ. Treated groups were compared to LPS/IFN-γ control group using ANOVA with Tukey’s post test (*, P <0.05; **, P < 0.001).