Table 2.
Haemodynamic data at baseline heart rate
| HFNEF (n = 17) | Controls (n = 7) | P-value | |
|---|---|---|---|
| Systolic function | |||
| End-systolic pressure (mmHg) | 133 (114–164) | 118 (111–130) | 0.172 |
| End-systolic volume (mL) | 27 (24–41) | 64 (30–74) | 0.181 |
| End-systolic volume index (mL/m2) | 21 (13–24) | 35 (18–38) | 0.054 |
| Ejection fraction (%) | 71 (63–76) | 66 (63–81) | 0.974 |
| End-systolic elastance (Ees) (mmHg/mL) | 1.79 (1.19–3.04) | 1.40 (1.26–1.65) | 0.312 |
| dP/dtmax (mmHg/s) | 1444 (1244–1748) | 1562 (1549–1866) | 0.153 |
| Diastolic function | |||
| End-diastolic pressure (mmHg) | 16.8 (13.1–20.2) | 6.3 (4.9–8.6) | <0.001 |
| End-diastolic volume (mL) | 108 (92–127) | 158 (114–182) | 0.019 |
| End-diastolic volume index (mL/m2) | 61 (51–68) | 76 (72–91) | 0.009 |
| τ (ms) | 55.3 (49.8–63.8) | 41.8 (36.3–42.6) | <0.001 |
| dP/dtmin (mmHg/s) | −1643 (−1924–−1364) | −1857 (−2084–−1577) | 0.325 |
| Stiffness constant β | 0.0245 (0.0203–0.0315) | 0.0107 (0.0089–0.0120) | <0.001 |
| Global cardiac function | |||
| Heart rate (b.p.m.) | 66 (60–68) | 72 (67–90) | 0.114 |
| Cardiac index (mL/min/m2) | 2812 (2570–2997) | 3980 (3066–4638) | 0.007 |
| Stroke volume index (mL/m2) | 44 (38–46) | 61 (43–63) | 0.061 |