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. Author manuscript; available in PMC: 2010 Nov 1.
Published in final edited form as: Gut. 2009 Jul 21;58(11):1538–1544. doi: 10.1136/gut.2008.171280

Table 5.

Follow-up liver biopsy (n = 5)

Patient
No.
Interval between 1st
and last liver biopsy
(months)
Date of liver biopsy
(month/date/ /year)
Steatosis
Grade
Lobular
inflammation
Grade
Fibrosis
Stage
Reason to repeat the liver
biopsy
1 33 1st biopsy
(3/1993)
Moderate Mild 1 -
2nd
Biopsy
(12/1995)
Moderate Mild 1 Follow up before
ursodeoxycholic acid
prescribed
2 57 1st biopsy
(7/1999)
Mild Mild 0 -
2nd
Biopsy
(2/2001)
Moderate Mild 1 Worsening of ALT levels
Last biopsy
(4/2004)
Severe Mild 4 Liver biopsy performed for
persistently elevated ALT and
done during laparoscopic
cholecystectomy
3 82 1st biopsy
(12/1996)
Mild Mild 0 -
2nd
Biopsy
(4/1999)
Moderate Mild 1 Persistent abnormal liver
tests
Last biopsy
(11/2002)
Moderate Moderate 3 Liver biopsy performed for
persistently elevated liver
enzymes and done during
bariatric surgery
4 28 1st
Biopsy
(8/1990)
Moderate Mild 0 -
2nd
Biopsy
(2/1991)
Moderate Mild 0 Persistent abnormal liver
tests
3rd
Biopsy
(12/1992)
Moderate Mild 1 Follow up before starting
treatment with
ursodeoxycholic acid
5 7 1st
Biopsy
(Oct 14,1998)
Mild 0 0 -
2nd
Biopsy
(10/1999)
Mild 0 1 Laparoscopic liver
biopsy during surgery for
persistent
patent ductus venosis.