Table 4. Multivariate Odds Ratios (ORs) with 95% Confidence Intervals (CIs) of Albuminuria by Type 2 Diabetes Status and Presence of Atherosclerosis, Excluding Subjects Using Hypertension Medication.
Type 2 Diabetes | No Diabetes | |||
---|---|---|---|---|
Marked Atherosclerosis†‡ 263 |
No Marked Atherosclerosis† 600 |
Marked Atherosclerosis†‡ 984 |
No Marked Atherosclerosis† 4055 |
|
JNC6 Blood Pressure (mmHg) Categories | P-trend = 0.008 | P-trend = 0.005 | P-trend=0.002 | P-trend<0.001 |
Optimal (reference) SBP<120 & DBP<80 |
1.00 | 1.00 | 1.00 | 1.00 |
Normal SBP 120-129 and DBP 80-84 |
5.93 (0.64 - 54.87) | 1.45 (0.59 - 3.59) | 1.42 (0.53 - 3.82) | 1.35 (0.78 - 2.32) |
High Normal SBP 130-139 or DBP 85-89 |
11.99 (1.33 - 108.18)* | 0.53 (0.15 - 1.84) | 0.77 (0.20 - 2.95) | 2.72 (1.62 - 4.58)*** |
Stage 1 Hypertension SBP 140-159 or DBP 90-99 |
13.23 (1.44 - 121.88)* | 1.98 (0.78 - 4.98) | 2.94 (1.12 - 7.70)* | 2.76 (1.61 - 4.73)*** |
Stage 2 and 3 Hypertension SBP≥160 or DBP≥100 |
14.08 (1.36 - 145.83)* | 7.67 (2.57 - 22.90)*** | 8.41 (2.59 - 27.29)*** | 6.68 (3.25 - 13.70)*** |
P< 0.05;
P<0.01;
P<0.001
Adjusted for age, gender, race, BMI, fasting glucose, insulin, triglycerides, HDL, GFR<90, and current smoking
Additionally adjusted for prevalent CHD