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Colocalization of p53 with apoptosis in cisplatin-treated renal cortical tissues. Renal cortical tissues were collected 3 days after cisplatin injection and subjected to p53 immunofluorescence and TdT-UTP nick end labeling (TUNEL) staining. A: representative image of p53 and TUNEL staining. Arrows: colocalization of p53 and TUNEL staining. B: percentages of TUNEL positive cells with or without p53 accumulation were determined by cell counting. Data are expressed as means ± SD (n = 4).
