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. Author manuscript; available in PMC: 2009 Dec 14.
Published in final edited form as: Am J Physiol Renal Physiol. 2007 Aug 1;293(4):F1282–F1291. doi: 10.1152/ajprenal.00230.2007

Fig. 4.

Fig. 4

Suppression of p53 activation during cisplatin treatment by pifithrin-α. C57BL/6 mice were treated for 3 days with cisplatin only or cisplatin together with 2.2 mg/kg pifithrin-α to collect renal tissues. A: immunoblot analysis of p53 and phospho-p53 (Ser15) in renal tissue lysates. B: immunofluorescence of p53 and phospho-p53 (Ser15) in renal cortex. Arrows: cells with p53 and phospho-p53 induction. The results are representatives of 4 separate experiments.